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Selected Publications

2021 | Development

Single-cell morphometrics reveals ancestral principles of notochord development.
Andrews TGR, Pönisch W, Paluch EK, Steventon BJ, Benito-Gutierrez E.
Development. 2021 Aug 15;148(16):dev199430. doi: 10.1242/dev.199430.

2021 | BMC Biology

The dorsoanterior brain of adult amphioxus shares similarities in expression profile and neuronal composition with the vertebrate telencephalon. Benito-Gutiérrez È, Gattoni G, Stemmer M, Rohr SD, Schuhmacher LN, Tang J, Marconi A, Jékely G, Arendt D.
BMC Biol. 2021 May 21;19(1):110. doi: 10.1186/s12915-021-01045-w.

2020 | Genes

The ADAR Family in Amphioxus: RNA Editing and Conserved Orthologous Site Predictions. Zawisza-Álvarez M, Pérez-Calles C, Gattoni G, Garcia-Fernàndez J, Benito-Gutiérrez È, Herrera-Úbeda C.
Genes (Basel). 2020 Nov 30;11(12):1440. doi: 10.3390/genes11121440.

2020 | Methods Mol Biol

Hybridization Chain Reaction for Quantitative and Multiplex Imaging of Gene Expression in Amphioxus Embryos and Adult Tissues. Andrews TGR, Gattoni G, Busby L, Schwimmer MA, Benito-Gutiérrez È.
Methods Mol Biol. 2020;2148:179-194. doi: 10.1007/978-1-0716-0623-0_11. PMID: 32394382.

2018 | BioRxiv

Patterning of a telencephalon-like region in the adult brain of amphioxus. Benito-Gutiérrez È, Stemmer M, Rohr SD, Schuhmacher LN, Tang Y, Marconi A, Jékely G, Arendt D


2018 | Nature

Amphioxus functional genomics and the origins of vertebrate gene regulation. Marlétaz F et al.
Nature. 2018 Dec;564(7734):64-70. doi: 10.1038/s41586-018-0734-6. Epub 2018 Nov 21. PMID: 30464347; PMCID: PMC6292497.

2017 | Nucleic Acids Res

Mirnovo: genome-free prediction of microRNAs from small RNA sequencing data and single-cells using decision forests. Vitsios DM, Kentepozidou E, Quintais L, Benito-Gutiérrez E, van Dongen S, Davis MP, Enright AJ. 
Nucleic Acids Res.2017 Dec 1;45(21):e177. doi:10.1093/nar/gkx836. PMID: 29036314; PMCID: PMC5716205.

2015 | Phil Trans Royal Soc

Gastric pouches and themucociliary sole: setting the stage for nervous system evolution. Arendt D, Benito-Gutierrez E, Brunet T, Marlow H.
Philos Trans R Soc Lond B Biol Sci. 2015 Dec 19;370(1684):20150286. doi: 10.1098/rstb.2015.0286. PMID: 26554050; PMCID: PMC4650134.

2013 | PLoS One

Methods for generating year-round access to amphioxus in the laboratory. Benito-Gutiérrez E, Weber H, Bryant DV, Arendt D.
PLoS One. 2013 Aug 26;8(8):e71599. doi: 10.1371/journal.pone.0071599. PMID: 23990962; PMCID: PMC3753313.

2012 | PNAS

Molecular analysis of the amphioxus frontal eye unravels the evolutionary origin of the retina and pigment cells of the vertebrate eye. Vopalensky P, Pergner J, Liegertova M, Benito-Gutierrez E, Arendt D, Kozmik Z.
Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15383-8. doi: 10.1073/pnas.1207580109. Epub 2012 Sep 4. PMID: 22949670; PMCID: PMC3458357.

2009 | Curr Biol

CNS evolution: new insight from the mud. Benito-Gutiérrez E, Arendt D. 
Curr Biol. 2009 Aug 11;19(15):R640-2. doi: 10.1016/j.cub.2009.06.020. PMID: 19674543.

2009 | Bioessays

It's a long way from amphioxus: descendants of the earliest chordate. Garcia-Fernàndez J, Benito-Gutiérrez E.
Bioessays. 2009 Jun;31(6):665-75. doi: 10.1002/bies.200800110.PMID:19408244.

2008 | Nature

The amphioxus genome and the evolution of the chordate karyotype. Putnam NH, et al.,
Nature. 2008 Jun 19;453(7198):1064-71. doi:10.1038/nature06967. PMID: 18563158.

2005 | Development

The single AmphiTrk receptor highlights increased complexity of neurotrophin signalling in vertebrates and suggests an early role in developing sensoryneuroepidermal cells. Benito-Gutiérrez E, Nake C, Llovera M, Comella JX, Garcia-Fernàndez J.

Development. 2005 May;132(9):2191-202. doi:10.1242/dev.01803. Epub 2005 Mar 30. PMID: 15799999.

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